Autoimmune patients expend considerable effort finding the right diet, supplements, lifestyle, and practitioner to manage their autoimmunity.

But did you know your experiences from childhood could be provoking your autoimmunity as an adult?

Abuse, belittlement, insults, neglect, loss of loved ones, parental acrimony… the traumas children weather unfortunately become a lifelong “operating system” that has profound influences on immunological and neurological health. Traumas in childhood affect not only physical and cellular health, but also our DNA.

Early traumas make it hard to turn off stress

In a healthy situation, a child can respond to stress and recover from it, developing normal resiliency.

However, chronic and unpredictable stress in childhood constantly floods the body with stress hormones and keeps it in a hyper vigilant inflammatory state. In time, this interferes with the body’s ability to turn off or dampen the stress response.

In fact, research that compared the saliva of healthy, happy children with children who grew up with abuse and neglect found almost 3,000 genetic changes on their DNA. All of these changes regulated the response to stress and the ability to rebound from it.

This means that little, everyday occurrences that might momentarily irritate a healthier person can unleash a torrent of stress hormones and an accompanying inflammatory cascade that predisposes one for disease.

These are the people accused of overreacting and who are rattled by loud noises, bright lights, and crowds.

A disagreement with someone, a near miss on the highway, a restaurant that’s too loud, an unexpected bill — for the person who had a stressful childhood these minor but regular insults create a metabolic environment that fosters and perpetuates illness.

This can include autoimmune disease, chronic pain, heart disease, cancer, fibromyalgia, chronic fatigue, digestive disorders, migraines, asthma, and obesity.

In fact, this research was inspired by one clinician’s observation that the majority of his obese patients endured sexual abuse as children.

Assessing chronic childhood stress

Researchers studied the effects of childhood stress on later health in the Adverse Childhood Experiences (ACE) Study, developing a short quiz to assess the relationship between childhood traumas and disease risk.

For instance, someone with a score of 4 (scale of 0–8) is at a significantly higher risk for chronic disease, suicide, and addiction.

Early trauma and autoimmune management

Although traumas during childhood and a higher ACE score can increase hardships and disease risk in adulthood, it doesn’t have to be a prison sentence —the brain and body are responsive to change.

Many therapies have been shown to help heal these traumas: meditation, mindfulness practices, neurofeedback, EMDR (eye movement desensitization and reprocessing), cognitive therapy, EFT (emotional freedom technique, or tapping), and more.

Be sure and include your emotional well-being and the health of your subconscious “operating system,” which was established in childhood, in your autoimmune management plan.

If you are managing your autoimmune disease through diet and lifestyle, then you probably know about the autoimmune diet  supplements, non-toxic home and body products, and getting enough rest.

But are you aware of hidden sources of stress that may be triggering autoimmune flares?

Common autoimmune diseases today include Hashimoto’s hypothyroidism, multiple sclerosis, type 1 diabetes, psoriasis, celiac disease, rheumatoid arthritis, and pernicious anemia. However, there are many more.

Research increasingly shows the connection between autoimmune disease and food sensitivities (such as to gluten) and environmental toxins. Indeed, many people have successfully sent their autoimmunity into remission by following an autoimmune diet and “going green” with the products they use.

We also know stress is inflammatory and can trigger autoimmunity. But what many people may miss is the hidden sources of this inflammation-triggering stress.

Little known triggers of autoimmune disease

Following are little known sources of stress that could be triggering autoimmune disease flare-ups:

Stressful TV shows: Turning on the flat screen to relax could backfire if you’re watching people always on the run from zombies. Research shows watching others stress out can raise our own stress hormones  On top of that, many people feel like failures after they watch TV, which is stressful. Try a productively calming hobby, like practicing an instrument or working with your hands while listening to music to calm your nerves … and your immune system.

Social media: Research shows social media users are more stressed out than non-users. Facebook and Twitter can make us feel like we always have to put on a happy face and that we’re not as successful as our friends. The addictive nature of social media is also stressful. As with all good things, practice moderation. And go see your friends in real life — socialization is a well-known stress buster and health booster that can help you better manage your autoimmune disease.

A bad relationship: We get so used to some relationships we don’t even realize they’re unhealthy. For instance, researchers have shown bad marriages are linked with more stress and inflammation. Bad bosses have also been shown to be hard on your health. Although it’s not so easy to just pop out of a bad relationship, being aware that it can trigger your autoimmune symptoms can help you start moving in a healthier direction.

A difficult childhood: Research shows links between a history of childhood adversities (neglect, disruption, trauma, abuse) and autoimmune disease. Chronic stress while the brain and central nervous system are still developing can create ongoing inflammation and set the stage for autoimmune disease to more easily trigger later in life.

Lack of self-love: How well you love and respect yourself influences your choice in relationships, your career, and how you handle problems. Do you talk to and treat yourself with the same kindness you would an adored child? Do you care for your needs the same way you do a pampered pet? If you bully yourself, you’re unwittingly triggering your autoimmunity. After all, autoimmune disease is the body attacking itself. Don’t foster that with self-attacking thoughts and behaviors. Commit to practicing small acts of self-love throughout your days.

When you look at issues like a bad childhood, a toxic relationship, or lack of self-love, it makes changing your diet and switching to natural body products look easy.

But that’s not the whole picture. Autoimmune disease is a flag from the body that certain aspects of your life may need evaluating and evolving.

Do you “crash” after a busy or stressful event, suffering from extreme exhaustion that keeps you confined to your bed or couch? Do these crashes last anywhere from a day to a week or even longer? If so, you’re not alone and you may suffer from autoimmunity, a condition in which the immune system attacks and destroys tissue in the body. (Which tissue depends on genetics and the type of autoimmunity you have.)

In fact, a recent survey of almost 8,000 autoimmune patients found the overwhelming majority listed bouts of debilitating fatigue as one of their most troubling symptoms.

Any number of things can cause a person with autoimmunity to “crash.” They can include a very stressful event, such as a car accident or a move. Pleasant events can cause crashes because they are long or exhausting, such as a wedding, a trip out of town, or a work conference. Many people hold up fine during the event but crash when it’s over. Exposure to certain foods or chemicals causes it in others.

Because such crashes are not commonplace or medically recognized, they cause anxiety and embarrassment. It’s like having the flu or a bad cold, except without the symptoms. Sufferers worry others will think they are lazy, another stressor on top of stressing about all the things not getting done because you’re in bed, barely able to function. Unfortunately, brain power bottoms out along with physical energy, which makes working at home from your laptop difficult if not impossible.

New survey brings light to autoimmune crashes

Fortunately, you may not have to make excuses for your inability to function forever as awareness about these bouts of debilitating fatigue grows. The survey polled those suffering from a variety of autoimmune diseases, such as Hashimoto’s hypothyroidism, rheumatoid arthritis, celiac disease, or autoimmunity affecting the brain or nervous system.

Overwhelming number of autoimmune patients report debilitating fatigue

The survey of patients with autoimmune disease, which was conducted by a patient advocacy group, revealed:

• 98 percent suffer from fatigue
• 89 percent said fatigue was a major issue
• 59 percent said fatigue was their most debilitating symptom
• Two-thirds said their fatigue was profound and prevented them from doing everyday tasks
• 75 percent said fatigue impacts their ability to work, 40 percent said it causes financial stress, and another one in five said it has cost them their jobs and they’re on disability
• The overwhelming majority reported fatigue not only impacts their professional life, but also their romantic and family life and self-esteem.
• The overwhelming majority also say it has resulted in emotional distress, isolation, anxiety, and depression.

According to one patient, “It’s difficult for other people to understand fatigue when it can’t be seen. It’s hard trying to get others, even doctors, to understand how very tired you are. One wonders if they think we are just mental cases or whiners.”

Fortunately, using functional medicine approaches can significantly improve your health and reduce the frequency and severity of these bouts of fatigue. Ask my office for more information.

BPA (bisphenol-A) is gaining recognition as an undesirable toxin that people now try to avoid in plastics, particularly water bottles. But it’s harder to avoid than you think – research shows handling those seemingly innocuous store receipts quickly raises blood levels of BPA.

BPA on store receipts

Store and fast food receipts, ATM receipts, airline tickets, gas station receipts, and other thermal papers use large amounts of BPA on the surface as a print developer. Holding a receipt coated with BPA for just five seconds is enough to transfer it to your skin and if your fingers are wet or greasy about 10 times as much is transferred. Having hand sanitizers, lotions, or sunscreen on your hands also increases the amount of BPA your body takes in from receipts. Cash stored with receipts in a wallet also become contaminated with BPA that raises blood levels when handled.

Why BPA is bad for health

So why should you care? BPA has estrogen-like qualities that meddle with hormone function and become a toxic burden. In rodents BPA has been proven to cause reproductive defects, cancer, and metabolic and immune problems. BPA is particularly threatening to a developing fetus as it can cause chromosomal errors, miscarriage, and genetic damage. In children and adults BPA is linked to decreased sperm quality, early puberty and early breast development, ovarian and reproductive dysfunction, cancer, heart disease, thyroid problems, insulin resistance, and obesity.

BPA and autoimmunity

Recent research also links BPA to the triggering and flaring of autoimmune disorders such as Hashimoto’s hypothyroidism. BPA does this because it stimulates and disrupts various pathways in the immune system, which raises the risk of triggering autoimmune disease or flare-ups.

Where BPA is found

BPA is the main component of polycarbonate and is also found in water and beverage bottles, plastic lids, the lining of tin cans, food storage containers, dental sealants, contact lenses, and electronics. BPA contamination from canned foods is significant. One study found a person who eats canned soup versus fresh soup receives 1,000 percent more BPA because it is in the lining of the can. Plastics exposed to heat, light, or acids (such as soda) release considerably more BPA. Eating from a microwaved plastic container and drinking hot coffee through a plastic coffee lid, sugary soda from a plastic water bottle, or water from a plastic bottle that has been sitting in the sun are examples of ways you will increase your exposure to BPA.

BPA-free is no guarantee

Given the documented health risks it poses, BPA has been banned from use in baby bottles and sippy cups and many companies now offer BPA-free products. Unfortunately, researchers have found many non-BPA plastics still have synthetic estrogens similar to BPA. Some even have more. Basically, if it’s plastic, it’s a problem–- 95 percent of all plastic products can disrupt hormones, even if they carry a “BPA-free” label. Also, be aware that some metal water bottles are lined with plastic, negating the purpose of avoiding a plastic water bottle.

How to reduce your exposure to BPA

It’s important to reduce your exposure to BPA as much as possible. Minimize use of plastics and especially avoid drinking or eating from heated plastic. Maintaining healthy gut bacteria with cultured and fermented foods such as kimchi and taking probiotics is believed to help mitigate the absorption of BPA and help degrade it in the body.

When it comes to battling inflammation and autoimmunity, research shows resveratrol and curcumin work better when taken together than separately.

Supplemental resveratrol is derived from Japanese knotweed and the compound is also found in the skin of red grapes. Curcumin is derived from the curry spice turmeric. Both are well known for their antioxidant, inflammation-quenching qualities when taken in therapeutic doses — simply eating curry or drinking wine are not going to impart much beneficial effect. Studies of the compounds look at large doses that can only come from supplementation.

Although each is a powerful anti-inflammatory alone, research shows that taking resveratrol and curcumin together creates a synergistic effect, making them potent tools for quenching the inflammation and damage associated with autoimmune flare-ups and chronic inflammation.

Resveratrol and curcumin combined battle autoimmune, inflammatory disorders

Examples of these disorders include autoimmune Hashimoto’s hypothyroidism, arthritis, brain fog, gut pain and inflammation, multiple food and chemical sensitivities, fibromyalgia, asthma, eczema and psoriasis, and other conditions related to inflammation or autoimmune disease.

Studies have increasingly spotlighted an important immune pathway in autoimmunity and inflammation called TH-17. While TH-17 helps defend us from viruses and bacteria, over activation of TH-17 triggers autoimmune flare-ups and chronic inflammation. When it comes to quenching these flare-ups, TH-17 is the target.

This is where resveratrol and curcumin come in, working together to dampen the activation of TH-17, thus protecting tissue from inflammation and damage.

Resveratrol and curcumin combat inflammation from excess body fat

One of the more unhealthy aspects of excess body fat is that it causes chronic inflammation that feeds autoimmune or inflammatory disorders. This is a double whammy for the person struggling with weight gain due to Hashimoto’s hypothyroidism. Research shows that resveratrol and curcumin in combination significantly reduce the inflammation caused by excess fat.

These two compounds have also been shown to help manage hair loss, psoriasis, joint disease, and other inflammatory disorders.

Immune regulation

Resveratrol and curcumin also support “regulatory T cells,” cells that regulate the immune system. When regulatory T cells don’t work efficiently, the immune system can become overzealous and promote inflammation and autoimmunity.

Other compounds that support regulatory T cells include vitamin D3, vitamin A, fish oil or krill oil, specific probiotic strains, nutrients that boost activity of glutathione  our master antioxidant, and nutrients that act on nitric oxide pathways.

Resveratrol curcumin combo is inflammation-quenching breakthrough

The research on TH-17 gives functional medicine practitioners new tools with which to better manage autoimmunity and chronic inflammation. Ask my office for advice on highly absorbable forms of curcumin and resveratrol in therapeutic amounts.